Somatostatin receptor 2
|Somatostatin receptor 2|
|RNA expression pattern|
Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR2 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney.
Most pituitary adenomas express SSTR2, but other somatostatin receptors are also found.< Somatostatin analogs (i.e. Octreotide, Lanreotide ) are used to stimulate this receptors, and thus to inhibit further tumor proliferation.
- Medical Subject Headings (MeSH)
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