Thiorphan

Thiorphan

Thiorphan
Systematic (IUPAC) name
(±)-2-[(2-benzyl-3-sulfanyl-propanoyl)amino]acetic acid
Clinical data
Legal status
?
Identifiers
CAS number  N
ATC code ?
PubChem
DrugBank
ChemSpider  YesY
ChEMBL  YesY
Chemical data
Formula C12H15NO3S 
Mol. mass 253.32 g/mol
 N   

Thiorphan is the active metabolite of the antidiarrheal racecadotril (acetorphan).[1] It prevents the degradation of endogenous enkephalins by acting as an enkephalinase inhibitor.[1]

See also

References

  1. ^ a b Spillantini MG, Geppetti P, Fanciullacci M, Michelacci S, Lecomte JM, Sicuteri F (June 1986). "In vivo 'enkephalinase' inhibition by acetorphan in human plasma and CSF". European Journal of Pharmacology 125 (1): 147–50.